Virginia City

After Cacopoulos manages to save himself from being hung on a false charge, he robs Cat Stevens and Hutch Bessy of a lot of money and steals their horses. This results in a merry chase and Stevens and Bessy become unwilling allies in Cacopoulus' revenge against the people who deserted him and framed him to get their money back.

Questions arise when Senator Stoddard attends the funeral of a local man named Tom Doniphon in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance. As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.

Kate Soffel is married to a prison warden in Pittsburgh, and is the mother of their four children. Ed Biddle is a convicted murderer awaiting execution on death row with his brother Jack. When Kate meets Eddie through her Bible readings to the prisoners, she is drawn to him, and they pursue a clandestine relationship. She agrees to help the brothers escape, and begins a treacherous journey with them to freedom in Canada.

Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".

A bounty hunter trying to bring a murderer to justice is forced to accept the help of two less-than-trustworthy strangers.

In post-war Germany, liberation by the Allies does not mean freedom for everyone. Hans Hoffmann is repeatedly imprisoned under Paragraph 175, which criminalizes homosexuality. Nevertheless, over the decades, he continues his quest for freedom and love, even if he finds it in the most unusual places.

John Russell, disdained by his "respectable" fellow stagecoach passengers because he was raised by Indians, becomes their only hope for survival when they are set upon by outlaws.

A young musician takes a beautiful tattoo artist on a ride in a stolen classic car.

When Rocklin arrives in a western town he finds that the rancher who hired him as a foreman has been murdered. He is out to solve the murder and thwart the scheming to take the ranch from its rightful owner.

Bounty hunters seek shelter from a raging blizzard and get caught up in a plot of betrayal and deception.