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During the Warring States period, the young thief Dororo encounters Hyakkimaru, a strange, sightless boy who wields fearsome prosthetics in place of his missing limbs. Parts of Hyakkimaru’s body were traded to a group of 12 demons by his father in exchange for power, but thanks to a kindly medicine man, Hyakkimaru survived his horrifying ordeal. Now he roams the land in search of his missing body, and together he and Dororo will fight to survive in an unforgiving, demon-plagued world.

Black Jack is an "unregistered" doctor with a clouded, mysterious past. He works with his little assistant Pinoko (who has a massive crush on the doctor), dealing with medical cases not very well known, which can be strange, dangerous, or not known at all. But he is a genius, and can save almost any of his patients' life (as long as they have the money for it, that is), and is known to many around the world, especially to those of medicine and science. He's a man of science himself, and does not believe much until he has seen it, yet it is many times he is surprised by love and nature often overpowering the science he bases his life in.

The Three-Eyed One is a romance SF manga by Osamu Tezuka. It was originally serialized in Weekly Shōnen Magazine from 7 July 1974 through 19 March 1978 and was later published into thirteen tankōbon by Kodansha. This story is about Hosuke Sharaku, the heir to the long lost super civilization of the "Three Eyed Ones", and his best friend, Chiyoko Wato, with whom he solves various problems, often of his own doing. In 1977, The Three-Eyed One tied with another Tezuka manga, Black Jack, for the Kodansha Manga Award. The manga has since spawned a TV special by Shueisha and later an anime whose 48 episodes ran from 18 October 1990 through 26 September 1991. The main character appears in three video games: Mittsume ga Tooru by Natsume on the MSX in 1989, Mittsume ga Tooru/The Three-Eyed One by Tomy on the NES in 1992, Astro Boy: Omega Factor by Sega on the Game Boy Advance and Astro Boy by Sega on the PlayStation 2.

Blue Blink is a fantasy adventure anime series created by Osamu Tezuka. The anime is based from classic film Konjok-gorbunok by Ivan Ivanov-Vano. The film in turn is based from Pyotr Pavlovich Yershov's The Little Humpbacked Horse. This was Tezuka's last anime series. Osamu Tezuka died while this series was in production. The studio completed the production according to his plans. The show is currently streaming at Anime Sols, but will soon be removed, because it did not meet its goal of crowd-funding the for DVD. It is alternately available for legal streaming at Viki.com.

The year is 1968, and the world is swept up in the Vietnam War and student protests. In this time of turmoil, a mysterious young man with white and black hair and a scar on his face is enrolled in medical school. His genius skills with a surgical knife achieve many a medical miracle and are getting noticed. This hero origin story reveals how this young man earned his medical degree and the name of Black Jack.

Astro is a robotic boy created by Dr. Tenma to replace his late son. When Tenma destroys his laboratory and shuts down Astro, the Ministry of Science revives him and tries to give him a normal life as a 6th-grade student who occasionally helps keep renegade robots from causing harm.

Princess Sapphire is a girl raised as a Prince. Through the mischief of an angel, the princess is born with both a girl's and a boy's heart. Since there is no boy successor in her kingdom, Sapphire is raised as a boy, but evil ministers try to reveal her secret. Unable to put up with the kind of vicious conduct prevailing in the kingdom, Sapphire disguises herself as "Princess Knight" and wields her sword of justice.

When the world's seven most advanced robots and their human allies are murdered one by one, Inspector Gesicht soon discovers that he's also in danger.

In 2030 AD, after being abandoned by his creator, a young boy robot is rescued by an Android Advocate, Dr Elefun, who adopts him as his own and guides him in the use of his special powers to aid and protect mankind and robot-kind.

2500 years ago, in India, Siddhartha was born as a prince of the Shakya clan, but he gives up his position as a prince to see the world. He meets a strange boy named Assaji, who can predict the future, a monk with only one eye and Depa. Siddhartha continues traveling. Siddhartha is overwhelmed by the sufferings he witnesses around him. Meanwhile, Prince Ruri of Kosara begins his attack on the Shakya clan. Second Buddha movie from Tezuka Productions.

Prince Siddhartha is heir to the Shakya kingdom, which is constantly at war with the more powerful Kosala kingdom. His father tries to raise as him as a warrior leader and to shield him from the miseries of the world. Meeting the young outcast girl Migaila, Siddhartha experiences love for the first time but also witnesses the suffering that afflicts humankind. Meanwhile, in Kosala, Chapra rises through the military, despite his lowly origins, to become a hero and general of the army. A final showdown between the two kingdoms forces Siddhartha to re-evaluate the path he is following.

The Galactic Federation is concerned about the number of wars on the Planet Earth. It sends three agents to determine if the planet is a potential threat to the universe, and whether it should be destroyed. The instrument of destruction is a device resembling a large black ball with two antennae that is variously called an anti-proton bomb, a solar bomb, and a neutron bomb. The agents (Captain Bokko, Nokko, and Pukko) are originally humanoid in appearance, but upon arrival on Earth they take on the appearances of a rabbit (Bokko), a horse (Nokko), and a duck (Pukko) that they had captured as examples of Earth life forms. While on Earth they travel in a tire-shaped vehicle capable of enormous speeds called the Big Wheel, which can travel on both land and water (and, with modifications, through the air)

In the midst of societal conflict in the futuristic city of Metropolis, Kenichi and his uncle Shunsaku Ban set out to uncover the mystery behind the first human-like robot, Tima.

In the year 2000, Dr. Boyton creates a super-robot in his deceased son's image. He calls the robot Astro Boy. Astro Boy can swim oceans, leap over mountains, even fly into space on his own power. However, Astro Boy can't replace his son. Dr. Boyton becomes dissatisfied with the boy robot and disowns him. Astro Boy is befriended by Dr. Packadermus J. Elefun of the Institute of Science, who guides him through his adventures. Endowed with super strength, rocket-powered flight, a selfless heart and a kind demeanor, Astro Boy fights a never-ending crusade against the forces of evil!

Tezuka Osamu's most famous work "Jungle Emperor Leo" has been made into an animated version a number of times. In this theater version, Tezuka Osamu was able for the first time to depict the theme that "All life is equal" through Leo's self-sacrifice.

When Unico, a young unicorn, is banished from his family by a pantheon of manipulative gods, his powers of joy and happiness are tested as he explores the lands with his friends Beezle and Katy.