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Awkward teenager Charlie Bartlett has trouble fitting in at a new high school. Charlie needs some friends fast, and decides that the best way to find them is to appoint himself the resident psychiatrist. He becomes one of the most popular guys in school by doling out advice and, occasionally, medication, to the student body.

Harvard Law student Oliver Barrett IV and music student Jennifer Cavilleri share a chemistry they cannot deny - and a love they cannot ignore. Despite their opposite backgrounds, the young couple put their hearts on the line for each other. When they marry, Oliver's wealthy father threatens to disown him. Jenny tries to reconcile the Barrett men, but to no avail.

Benjamin is meant to be a great doctor, he’s certain of it. But his first experience as a junior doctor in the hospital ward where his father works doesn’t turn out the way he hoped it would. Responsibility is overwhelming, his father is all but present, and his co-junior partner, a foreign doctor, is far more experimented than he is. This internship will force Benjamin to confront his limits… and start his way to adulthood.

Reckless playboy Bob Merrick crashes his speedboat, requiring emergency attention from the town’s only resuscitator while a local hero, Dr. Phillips, dies waiting for the life-saving device. Merrick then tries to right his wrongs with the doctor’s widow, Helen, falling in love with her in the process.