Splice

Splice

She's not human...not entirely.

R 2010 · 104 min · ★ 5.9 (3K) · Horror, Science Fiction

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Directed by Vincenzo Natali · Written by Antoinette Terry Bryant

Your Rating

Where to Watch

Rent or Buy

Google Play MoviesYouTube

Cast

Trailers & Videos

Make it a double feature

3h 32m together

Both from Vincenzo Natali.

More from Vincenzo NataliSee all →

TremorsTremors · 2018
Tremors
8.52018
SeriesComedySci-Fi & Fantasy
25 years after the movie, the prehistoric subterranean monsters known as Graboids return to Perfection, Nevada.
HannibalHannibal · 2013
Hannibal
8.32013
SeriesDramaCrime
Both a gift and a curse, Graham has the extraordinary ability to think like his prey—he sees what they see, feels what they feel. But while Graham is pursuing an especially troubling, cannibalistic murderer, Special Agent Jack Crawford teams him with a highly respected psychiatrist – a man with a taste for the criminal minded – Dr. Hannibal Lecter.
WestworldWestworld · 2016
Westworld
8.02016
SeriesSci-Fi & FantasyWestern
A dark odyssey about the dawn of artificial consciousness and the evolution of sin. Set at the intersection of the near future and the reimagined past, it explores a world in which every human appetite, no matter how noble or depraved, can be indulged.
Orphan BlackOrphan Black · 2013
Orphan Black
7.82013
SeriesDramaSci-Fi & Fantasy
A streetwise hustler is pulled into a compelling conspiracy after witnessing the suicide of a girl who looks just like her.
Locke & KeyLocke & Key · 2020
Locke & Key
7.72020
SeriesSci-Fi & FantasyDrama
After their dad's murder, three siblings move with their mom to his ancestral estate, where they discover magical keys that unlock powers — and secrets.
The PeripheralThe Peripheral · 2022
The Peripheral
7.62022
SeriesSci-Fi & FantasyDrama
Stuck in a small Appalachian town, a young woman’s only escape from the daily grind is playing advanced video games. She is such a good player that a company sends her a new video game system to test…but it has a surprise in store. It unlocks all of her dreams of finding a purpose, romance, and glamour in what seems like a game…but it also puts her and her family in real danger.
Lost in SpaceLost in Space · 2018
Lost in Space
7.52018
SeriesSci-Fi & FantasyAction & Adventure
After crash-landing on an alien planet, the Robinson family fights against all odds to survive and escape. But they're surrounded by hidden dangers.
The StrainThe Strain · 2014
The Strain
7.52014
SeriesSci-Fi & FantasyDrama
A high concept thriller that tells the story of Dr. Ephraim Goodweather, the head of the Center for Disease Control Canary Team in New York City. He and his team are called upon to investigate a mysterious viral outbreak with hallmarks of an ancient and evil strain of vampirism. As the strain spreads, Eph, his team, and an assembly of everyday New Yorkers, wage war for the fate of humanity itself.
Guillermo del Toro's Cabinet of CuriositiesGuillermo del Toro's Cabinet of Curiosities · 2022
Guillermo del Toro's Cabinet of Curiosities
7.52022
SeriesDramaMystery
Bizarre nightmares unfold in eight tales of terror in this visually stunning, spine-tingling horror collection curated by Guillermo del Toro.
Getting GilliamGetting Gilliam · 2005
Getting Gilliam
7.32005
MovieDocumentary
This documentary follows director Terry Gilliam through the process of making his film Tideland.
Space CasesSpace Cases · 1996
Space Cases
7.11996
SeriesDramaSci-Fi & Fantasy
Space Cases is a science fiction television series. Its premise revolves around a group of misfit students and two adults who are stranded far from home aboard an alien ship. Their attempts at journeying back see many dangerous adventures and controversies, with some occasionally more mature themes.
American GodsAmerican Gods · 2017
American Gods
7.12017
SeriesDramaMystery
An ex-con becomes the traveling partner of a conman who turns out to be one of the older gods trying to recruit troops to battle the upstart deities. Based on Neil Gaiman's fantasy novel.
Hemlock GroveHemlock Grove · 2013
Hemlock Grove
7.12013
SeriesMysteryDrama
One cannot quench his all-consuming thirst. The other cannot tame the beast clawing its way out. In the sleepy Pennsylvania village of Hemlock Grove, two young men struggle to accept painful truths: about family, themselves, the mystery of the White Tower - and a terrifying new threat so powerful it will turn them from predators into prey.
Marvel's Luke CageMarvel's Luke Cage · 2016
Marvel's Luke Cage
6.92016
SeriesDramaAction & Adventure
Given superstrength and durability by a sabotaged experiment, a wrongly accused man escapes prison to become a superhero for hire.
Ginger SnapsGinger Snaps · 2000
Ginger Snaps
6.92000
MovieHorrorFantasy
The story of two outcast sisters, Ginger and Brigitte, in the mindless suburban town of Bailey Downs. On the night of Ginger's first period, she is savagely attacked by a wild creature. Ginger's wounds miraculously heal but something is not quite right. Now Brigitte must save her sister and save herself.
Wayward PinesWayward Pines · 2015
Wayward Pines
6.92015
SeriesDramaMystery
Imagine the perfect American town... beautiful homes, manicured lawns, children playing safely in the streets. Now imagine never being able to leave. You have no communication with the outside world. You think you're going insane. You must be in Wayward Pines.

More Like This

GattacaGattaca · 1997
Gattaca
7.61997
MovieScience FictionDrama
Vincent is an all-too-human man who dares to defy a system obsessed with genetic perfection. He is an "In-Valid" who assumes the identity of a member of the genetic elite to pursue his goal of traveling into space with the Gattaca Aerospace Corporation.
Dark CityDark City · 1998
Dark City
7.31998
MovieMysteryScience Fiction
A man struggles with memories of his past, including a wife he cannot remember, in a nightmarish world with no sun and run by beings with telekinetic powers who seek the souls of humans.
Jacob's LadderJacob's Ladder · 1990
Jacob's Ladder
7.41990
MovieDramaMystery
After returning home from the Vietnam War, veteran Jacob Singer struggles to maintain his sanity. Plagued by hallucinations and flashbacks, Singer rapidly falls apart as the world and people around him morph and twist into disturbing images. His girlfriend, Jezzie, and ex-wife, Sarah, try to help, but to little avail. Even Singer's chiropractor friend, Louis, fails to reach him as he descends into madness.
InnerspaceInnerspace · 1987
Innerspace
6.81987
MovieActionComedy
Test pilot Tuck Pendleton volunteers to test a special vessel for a miniaturization experiment. Accidentally injected into a neurotic hypochondriac, Jack Putter, Tuck must convince Jack to find his ex-girlfriend, Lydia Maxwell, to help him extract Tuck and his ship and re-enlarge them before his oxygen runs out.
The Philadelphia ExperimentThe Philadelphia Experiment · 1984
The Philadelphia Experiment
6.11984
MovieScience FictionAdventure
Based on an "actual event" that took place in 1943. About a US Navy Destroyer Escort that disappeared from the Philadelphia Naval Shipyard, and sent two men 40 years into the future to 1984.
BrazilBrazil · 1985
Brazil
7.71985
MovieComedyScience Fiction
Low-level bureaucrat Sam Lowry escapes the monotony of his day-to-day life through a recurring daydream of himself as a virtuous hero saving a beautiful damsel. Investigating a case that led to the wrongful arrest and eventual death of an innocent man instead of wanted terrorist Harry Tuttle, he meets the woman from his daydream, and in trying to help her gets caught in a web of mistaken identities, mindless bureaucracy and lies.
Blade RunnerBlade Runner · 1982
Blade Runner
7.91982
MovieScience FictionDrama
In the smog-choked dystopian Los Angeles of 2019, blade runner Rick Deckard is called out of retirement to terminate a quartet of replicants who have escaped to Earth seeking their creator for a way to extend their short life spans.
AkiraAkira · 1988
Akira
7.91988
MovieAnimationScience Fiction
A secret military project endangers Neo-Tokyo when it turns a biker gang member into a rampaging psychic psychopath that only two teenagers and a group of psychics can stop.
Jurassic ParkJurassic Park · 1993
Jurassic Park
8.01993
MovieAdventureScience Fiction
A wealthy entrepreneur secretly creates a theme park featuring living dinosaurs drawn from prehistoric DNA. Before opening day, he invites a team of experts and his two eager grandchildren to experience the park and help calm anxious investors. However, the park is anything but amusing as the security systems go off-line and the dinosaurs escape.
The Lost World: Jurassic ParkThe Lost World: Jurassic Park · 1997
The Lost World: Jurassic Park
6.61997
MovieAdventureAction
Four years after Jurassic Park's genetically bred dinosaurs ran amok, multimillionaire John Hammond shocks chaos theorist Ian Malcolm by revealing that he has been breeding more beasties at a secret location. Malcolm, his paleontologist ladylove and a wildlife videographer join an expedition to document the lethal lizards' natural behavior in this action-packed thriller.
Jurassic Park IIIJurassic Park III · 2001
Jurassic Park III
6.22001
MovieAdventureThriller
In need of funds for research, Dr. Alan Grant accepts a large sum of money to accompany Paul and Amanda Kirby on an aerial tour of the infamous Isla Sorna. It isn't long before all hell breaks loose and the stranded wayfarers must fight for survival as a host of new -- and even more deadly -- dinosaurs try to make snacks of them.
The BlobThe Blob · 1988
The Blob
6.91988
MovieHorrorScience Fiction
In Arborville, California, three high school students try to protect their hometown from a gelatinous alien life form that engulfs everything it touches.
Spy Kids 2: The Island of Lost DreamsSpy Kids 2: The Island of Lost Dreams · 2002
Spy Kids 2: The Island of Lost Dreams
5.62002
MovieFamilyAction
Exploring the further adventures of Carmen and Juni Cortez, who have now joined the family spy business as Level 2 OSS agents. Their new mission is to save the world from a mad scientist living on a volcanic island populated by an imaginative menagerie of creatures. On this bizarre island, none of the Cortez's gadgets work and they must rely on their wits--and each other--to survive and save the day.
Red DragonRed Dragon · 2002
Red Dragon
7.02002
MovieCrimeThriller
Former FBI Agent Will Graham, who was once almost killed by the savage Hannibal 'The Cannibal' Lecter, now has no choice but to face him again, as it seems Lecter is the only one who can help Graham track down a new serial killer.
DarkmanDarkman · 1990
Darkman
6.41990
MovieActionScience Fiction
Dr. Peyton Westlake is on the verge of realizing a major breakthrough in synthetic skin when his laboratory is destroyed by gangsters. Having been burned beyond recognition and forever altered by an experimental medical procedure, Westlake becomes known as Darkman, assuming alternate identities in his quest for revenge and a new life with a former love.
An American Werewolf in ParisAn American Werewolf in Paris · 1997
An American Werewolf in Paris
5.91997
MovieHorrorComedy
An American man unwittingly gets involved with werewolves who have developed a serum allowing them to transform at will.
SoldierSoldier · 1998
Soldier
6.41998
MovieScience FictionAction
Sergeant Todd is a veteran soldier for an elite group of the armed forces. After being defeated by a new breed of genetically engineered soldiers, he is dumped on a waste planet and left for dead. He soon interacts with a group of crash survivors who lead out a peaceful existence. The peace is broken as the new soldiers land on the planet to eliminate the colony, which Sergeant Todd must defend.

Rate this film

Your ratings make Midnight smarter