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A down-on-his-luck crab fisherman embarks on a journey to get a young man with Down syndrome to a professional wrestling school in rural North Carolina and away from the retirement home where he’s lived for the past two and a half years.

At The Kingdom, Denmark's most technologically advanced hospital, a number of strange and otherworldly events begin occurring, much to the dismay of its doctors and patients. A ghostly ambulance appears and disappears, the voice of a little girl calls to a patient in an elevator shaft, and a doctor's fetus begins growing at an alarming rate.

Alba has Down's Syndrome and was left in the hospital when she was born. Thirty families rejected her before the court decided to entrust her to Luca: a Catholic — and gay — single man.

An unusual and wonderful friendship develops between a busy but unhappy salesman and a resident of a mental asylum.