Barry Schreiber

A scientist at a Florida university inadvertently creates a "rage virus" while performing experiments intended to restore dead brain tissue in baboons. When a journalist for the college paper breaks into the campus lab, he's bitten by one of the infected baboons; the virus soon spreads to a trio of rapists and a valley girl, all of whom go on killing sprees.

Bull Webster is a taxi driver with some work problems on his hands: the Spider Corporation, a giant financial holding company, has decided to buy out his taxi co-operative in order to make it go bankrupt and purchase its land at a low cost.

In Miami, Florida, biker gang leader Edward "Diablo" Santer is about to be executed for murder when he proclaims his innocence and vows revenge from the grave. When a mysterious biker comes to town during Spring Break festivities, leaving several teenagers electrocuted to death, some begin to suspect that Santer has made good on his promise.

Jack Costello is a retired cop and now private detective who lives in Miami, who handles a myriad of cases for unusual clients. At his side are old police buddy Sam Bosley and cartoonist-turned-amateur sleuth Jean Philippe Dumas, who is using Costello as an influence and has nicknamed the burly detective "Extralarge." In the second series, Costello faces other dangerous cases, again with Bosley and Archibald, the son of an old friend, who Costello amusingly nicknames "Dumas."