Justin R.G. Holcomb

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

The New York office of the FBI brings to bear all their talents, intellect and technical expertise on major cases in order to keep their city and the country safe.

Former Syracuse, New York, police detective Carrie Wells has hyperthymesia, a rare medical condition that gives her the ability to visually remember everything. She reluctantly joins the New York City Police Department's Queens homicide unit after her former boyfriend and partner asks for help with solving a case. The move allows her to try to find out the one thing she has been unable to remember, which is what happened the day her sister was murdered.